Chemical News
Engineered Pseudomonas putida monoculture system for green synthesis of 7-methylxanthine
DOI: 10.1039/D5GC02883C, PaperBhagya Jayantha, Shuyuan Zhang, Ryan M. Summers, Gamini P. Mendis, Lahiru N. Jayakody
Engineered Pseudomonas putida monoculture efficiently converts caffeine to 7-methylexanthine (7-MX), a clinically proven safe drug for treating myopia.
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Effective and scalable mechanochemical synthesis of platinum(II) heteroleptic anticancer complexes
DOI: 10.1039/D5GC02781K, PaperFatin Rashid, Christopher P. Gordon, Jennette A. Sakoff, Jayne Gilbert, Felipe García, Janice R. Aldrich-Wright
A robust mechanochemical strategy enables rapid and scalable synthesis of platinum(II) anticancer complexes. This greener method reduces solvent use, boosts energy efficiency, cuts costs and promotes sustainable metal complex production.
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Synthesis and characterization of a 3-hydroxybutyrate and 3-hydroxy-9-octadecenoate copolymer from engineered Halomonas
DOI: 10.1039/D5GC02422F, PaperXinyu Chen, Jiangnan Chen, Xu Yan, Qiong Wu, Fuqing Wu, Guo-Qiang Chen
A new copolymer of 3-hydroxybutyrate and 3-hydroxy-9-octadecenoate produced using recombinant Halomonas bluephagenesis is reported. The properties of this copolymer are characterized, and its potential applications are demonstrated.
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Polyphenolic nanomaterials ameliorated salmonellosis via barrier restoration and microbiota regulation
DOI: 10.1039/D5GC01363A, PaperTianyou Wang, Jinhong Dong, Bo Liang, Jianhua Zhang, Weijie Liu, Hengjie Zhang, Lei Yang, Yiwen Li, Xianchun Chen, Zhipeng Gu
Polyphenolic nanomaterials were developed for ciprofloxacin delivery, enhancing antibacterial efficacy while protecting gut health through green synthesis, minimizing side effects, and promoting intestinal barrier and microbiota recovery.
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Application and mechanism of various modified nano zero-valent iron in wastewater treatment: a critical review
DOI: 10.1039/D5GC02077H, Critical ReviewWei Teng, Kang Yang, Junhui Chen, Hongji Li, Junwei Han
This review systematically summarizes the nZVI modification strategies and their enhanced contaminant removal mechanisms for improved wastewater treatment.
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Life-cycle environmental impacts of typical plasticizers for plastics and their sustainable transformation potential
DOI: 10.1039/D5GC01960E, PaperYijun Li, Kai Zhao, Chi Wang, Hang Fu, Shanying Hu
This study presents a comparative life cycle assessment of 12 commonly used plasticizers, highlighting key differences in their environmental profiles and identifying promising candidates for green substitution.
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Performance and structural evolution of a new critical raw material-free catalyst, synthesized from spent lithium-ion batteries, for solar-driven CO2 conversion
DOI: 10.1039/D5GC02583D, Paper


A new critical raw material-free malate catalyst originating from spent lithium-ion batteries was prepared. It shows high catalytic performance for CO2 conversion.
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Making polymers with low carbon content: a sustainable option
DOI: 10.1039/D5GC02706C, PerspectiveYanni Xia, Chengjian Zhang, Xinghong Zhang
To address challenges from petroleum-based polluting polymers, we propose partial substitution of polymer carbon with oxygen (or sulfur) and biomass carbon to construct low-carbon polymers.
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Assessing mass intensity as a green chemistry metric: why expanding system boundaries is not enough
DOI: 10.1039/D5GC02994E, Paper


This study investigates under which circumstances the common practice of using mass intensities as proxies for environmental impacts is suitable—and where it fails.
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The use of a dynamic solvent system as a novel approach to sustainable MOF crystallization
DOI: 10.1039/D5GC01029B, Paper


Instead of the toxic and strictly regulated dimethylformamide, a dynamic solvent system containing an alcohol and a carboxylic acid is used for the synthesis, enabling the production of high-quality MOFs alongside valuable esterification products.
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Correction: Advancing solar-driven redox processes: pyrene-based covalent organic frameworks for efficient environmental remediation and H2O2 production
Green Chem., 2025, 27,10033-10033
DOI: 10.1039/D5GC90151K, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yaxuan Zheng, Siyu Han, Yuxin Sun, Zhangpei Chen, Yuqiu Huo, Jianshe Hu
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DOI: 10.1039/D5GC90151K, Correction


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Correction: Atom-efficient aldol condensation via magnetically recyclable nanoreactors: sol–gel imprinting enables template-switchable triple selectivity
Green Chem., 2025, 27,10032-10032
DOI: 10.1039/D5GC90150B, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ya Liu, Haiyan Jing, Yi Hao, Xuemeng Tian, Yue Wang, Xueyi Liu, Ruixia Gao
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DOI: 10.1039/D5GC90150B, Correction


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Copper-catalyzed amidoalkylation of amines via C–C bond cleavage from cyclic oxaziridines
DOI: 10.1039/D5GC03001C, CommunicationXin-Xin Liu, Shaohong Wang, Yuan Zhang, Fan Yang, Hong-Jie Miao, Peng-Chen Ma, Li-Na Guo, Pin Gao
We have successfully established an efficient copper-catalyzed C–C bond cleavage of cyclic oxaziridines and the C(sp3)-N coupling reaction with amines under mild and redox neutral conditions with 100% atom-economy.
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Advancing lignocellulosic conversion though biosensor-enabled metabolic engineering
DOI: 10.1039/D5GC03618F, Tutorial Review


Biosensor-aided metabolic engineering is advancing the conversion of lignocellulosic biomass by enabling regulation and optimization of microbial production pathways.
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Photoinduced carbonylative multicomponent reaction of anilines and arylaldehydes
DOI: 10.1039/D5GC02973B, Communication


A photoinduced carbonylative amination strategy with arylaldehydes, enabling the efficient synthesis of valuable α-aminoketones has been developed.
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Phosphatidylcholine-driven cell-like assembly of lignin for reinforcing and toughening rubber materials
DOI: 10.1039/D5GC01947H, PaperJunqi Zhang, Jianlong Wen, Zhenwei Liu, Fangwei Ling, Zhengtian Xie, Yijing Nie, Jinrong Wu
This work employs phosphatidylcholine to modulate the polarity of lignin, enabling lignin to form a self-assembled ‘cell-like structure’ within HPIP. The resulting composites achieve a remarkable strength of 26 MPa while maintaining excellent recycling capability.
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Utilisation of reactive ionic liquids for energy storage and regulation of the power grid
DOI: 10.1039/D5GC02519B, Perspective


Chlorine is an essential feedstock for polymers and pharmaceuticals, with annual production exceeding 100 Mt.
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N,Se co-doping strategy to boost the K+ storage performance of metal organic framework-derived 3D amorphous carbon
DOI: 10.1039/D5GC01554E, PaperYuyu Wang, Liangqin Cai, Shuo Yuan, Lin Feng, Zhen Guo, Shihua Dong
NSeC material with a high content of edge N and abundant micropores is synthesized, and shows fast potassium storage capabilities, promoted by the pseudo-capacitive effect, enhanced kinetics, and high structural stability.
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Closed-loop electro-upcycling of PET waste into formate and hydrogen via self-supported NiCo2O4 spinel arrays
DOI: 10.1039/D5GC01993A, PaperMingkun Jiang, Yang Yang, Yujie Wang, Yajie Wang, Marina Ratova, Dan Wu
NiCo2O4 electrocatalyst upcycles PET to formate (96.7% FE) and H2 at 400 mA cm−2, giving $774.56 per ton PET. Ni–Co sites cleave C–C bonds while limiting overoxidation, enabling sustainable plastic valorization.
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Visible-light-induced and EDA complex-driven multicomponent reaction: a strategy for the synthesis of α-CF3-β-phosphorodithioate tertiary alcohols
DOI: 10.1039/D5GC01349F, PaperMengqing Wang, Ziren Chen, Fei Xue, Qianqian Tan, Bin Wang, Yonghong Zhang, Yu Xia, Shaofeng Wu, Weiwei Jin, Xuefeng Jiang, Chenjiang Liu
A practical, environmentally friendly, visible-light-driven and EDA complex-promoted method for the synthesis of α-trifluoromethyl-β-phosphorodithioate tertiary alcohols in the absence of metals, photocatalysts and oxidants has been reported.
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